Rejuran vs Skinboosters Cost Guide Singapore review |绿珠兰

Rejuran Singapore is a new concept of skin healing booster that regenerates skin cells from deep inside by activating fibroblast proliferation and collagen synthesis.

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Rejuran healer review and cost

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What is RejuranHealer treatment?

Rejuran is a new concept of skin healing booster that regenerates skin cells from deep inside by activating fibroblast proliferation and collagen synthesis.

What is in RejuranHealer?

Salmon DNA.

Does RejuranHealer really work?

It does more than skin hydration. It also helps with skin repair, healing.

How long does RejuranHealer last?

Rejuran lasts 6 – 12 months after a a course of 3 sessions.

What are patient RejuranHealer reviews?

In my clinical experience, having performed hundreds of rejuran healer treatments, I can safely say that it has a near 99% satisfaction rate with my patients. Many can feel and see the difference in their skin quality, from tone, texture and colour.

What is Rejuran Healer cost in Singapore?

Prices vary across the board, depending on experience of your surgeon and whether the treatment is performed via a machine or manually.

When it first came out 2ml syringe would start from $800. Currently, last checked in experienced hands, prices start from $699.

What are Singaporeans biggest concerns regarding Rejuran Singapore?

Singaporeans dont like pain. Rejuran via manual injection can be rather tender.

Over the years, I have had 1 patient requesting for rejuran without numbing. We used ice for her. It was not the most comfortable.

In my clinical practice, I use certain techniques to reduce the pain sensation and make the treatment more comfortable.

What is the anti ageing craze in Korea?

Here is the background. A skin rejuvenation treatment took Korea by storm more than a year ago, with Korean celebrities  flocking to clinics to have this treatment on a regular basis. Korean women in their 30’s~50’s are so into REJURAN HEALER | REJURAN Review| REJURAN KOREA | REJURAN SINGAPORE that we have to discuss it here today. Simply the hottest treatment in town. and in Singapore, it IS the hottest treatment.

What is REJURAN HEALER and how does it work?

  1. It is a Polyneucleotide filler, aka a DNA filler. Polynucleotides are scientifically proven to assist with wound healing.
  2. REJURAN HEALER delivers DNA extracts ( polyneucleotides) into your skin. This repairs damaged dermal cells and keeps your skin healthy. In 7 days from the initial injection, you can feel your skin smoother and can notice enhanced firmness after 4 weeks.
  3. It gradually improves the general appearance and condition of your skin, keeping  your skin young and healthy. This is something that other fillers cannot do. This injection is recommended as an anti-aging treatment.

What is the difference between Rejuran Singapore, Skinboosters and botox treatments?

  1. REJURAN HEALER: Repairs damaged skin dermal cells, keeping your skin young healthy and supple
  2. SKIN BOTOX:  softening wrinkles
  3. HYALURONIC ACID based SKINBOOSTERS: Keeps dermis moisturized for longer time. Mainly for hydration.

Can REJURAN be combined with other treatments?

Combination treatment is the rage in Korea, Taiwan and here in Singapore. Many of you are currently undergoing treatments for various indications. The good news is yes. Rejuran enhances the efficacy of your existing treatments. These are the hottest combination treatments for rejuran presently.

  1. ACNE | ACNE SCARS – Rejuran is used together with microbotox to reduce oil production and skin redness.
  2. WHITENING – Rejuran is combined with laser toning to enhance skin brightening and whitening.
  3. NECK LINES | FOREHEAD LINES – Rejuran is combined with microbotox and dermal fillers to soften those extremely hard to treat neck lines.
  4. DARK EYE CIRCLES – Rejuran-i is deposited in microdroplets to reduce appearance of dark eye circles.
  5. ANTI AGEING – Personally, in my experience, I find combination of Rejuran with my proprietary boosters achieves very good anti ageing results.
REJURAN Singapore
Watch the Rejuran video here

What are the benefits of Rejuran healer?

It is derived from Salmon fish germ cell extract. It can help in the following?

  1. Protecting skin cells and improving skin tone and elasticity – smoother, firmer skin
  2. Skin brightening effect
  3. Repairing damaged dermal cells, keeping your skin young and healthy

Can Rejuran be combined with other treatments?

Due to its superior safety & efficacy, Rejuran Filler can be combined with other treatments. It can also be used alone to bring natural revitalization of the skin. In my practice, I combine Rejuran with other ingredients to give my patients the best results.

How is it done?

  1. Numbing cream is applied.
  2. Microinjector machine is used to deposit tiny amounts under the skin.

 What can I expect after treatment and what are the side effects?

  • Immediately after the injections, the skin at the injection site may swell up; but this will go away in about 1 or 2 days.
  • Injection marks are temporary.
  • Mild degrees of temporary redness, swelling and small risk of bruising.

After a week

  1. Brighter skin tone
  2. Colour and clarity improved

After 1 month

  1. Pore reduction
  2. Better oil and water balance. Reduced sebum.
  3. Improved overall skin condition

After 1 complete cycle

  1. Texture improved through neo-collagenesis, resulting in smoother skin
  2. Recovers faster from inflammation, pimples
  3. Skin looks noticeably healthier, brighter, and firmer

Are there REJURAN Before and After pictures?

As per MOH guidelines, we do not post before after pictures. However, we can share with you more information at consultation.

So what is the clinical evidence for Rejuran for skin rejuvenation?

We  know that fillers are not only for volumising, they also have a role in skin hydration and rejuvenation.

Let me first discuss skinboosters, and share with you the evidence behind it.

Evidence 1

Kim et al 2014[1] conducted a study on 150 patients who had 1,000 injections of 1 cc Skinboosters-HA by injector gun. The patients were examined after 1, 2, 6, 12, and 24 months. Changes in skin texture were determined with regard to skin roughness and morphology, dermal hydration by electric resistance, dermal thickness by ultrasonic imaging, and biopsy. An intra-individual study was also performed to compare changes in skin texture between dermal and subdermal injections.

Results show that the skin texture, hydration and thickness significantly improved after this procedure. The dermis of the face and hand were thickened about 4% after dermal injection. The injection depth was confirmed by biopsy. Injections into the dermis changed both skin texture and thickness.

Evidence 2

Park, Kui Young, et al 2016 [2] conducted a study on skin rejuvenation with Rejuran.

5 Korean women received 4 injections of long-chain PN filler in two-week intervals for skin rejuvenation. 0.05 mL of material was injected in 40 points on each side of the cheek. The pore and skin thickness were markedly improved in the patients in their 30s, whereas skin tone, melanin, wrinkles, and sagging were noticeably improved for patients in their 40s. There are no serious side effects. In conclusion, intradermal long-chain PN filler injection seems to be an effective and safe treatment for skin rejuvenation.

Evidence 3

Pak, Chang Sik, et al 2014[3] conducted a clinical trial and animal study comparing Rejuran to a Hyaluronic acid based filler.

In the clinical trial, 72 patients were randomized to receive Rejuran® treatment for crow’s feet on one side and Yvoire-Hydro® on the contralateral side, at a ratio of 1:1. Repeated treatments were performed every two weeks for a total of three times, over a total of 12 weeks’ observation. All injections and observations of efficacy and safety were performed by the same two investigators.

In the animal study, the Rejuran® group showed similar durability and inflammatory response to the Yvoire® group.Upon efficacy assessment, the Rejuran® group showed the greatest elasticity and collagen composition, and a significant difference in skin surface roughness and wrinkle depth. In the clinical trial, the primary and secondary objective efficacy outcome measure showed no statistical significance between the two groups, and in safety outcomes there were no unexpected adverse effects.


In summary, there is a role for hyaluronic acid skinboosters and polyneucleotide fillers in skin rejuvenation. Existing studies are a handful primarily because these treatments are relatively new. As the studies are of a smaller scale, and of lower quality, larger and more robust clinical trials are required to better evaluate the safety and efficacy of such treatments, especially so for the polyneucleotide filler.

So I hope this has been helpful.

Dr Daniel Chang

[1] Kim, Jongseo. “Effects of injection depth and volume of stabilized hyaluronic acid in human dermis on skin texture, hydration, and thickness.” Archives of Aesthetic Plastic Surgery 20.2 (2014): 97-103.
[2] Park, Kui Young, et al. “Long‐chain polynucleotide filler for skin rejuvenation: efficacy and complications in five patients.” Dermatologic therapy 29.1 (2016): 37-40
[3] Pak, Chang Sik, et al. “A Phase III, Randomized, Double-Blind, Matched-Pairs, Active-Controlled Clinical Trial and Preclinical Animal Study to Compare the Durability, Efficacy and Safety between Polynucleotide Filler and Hyaluronic Acid Filler in the Correction of Crow’s Feet: A.” Journal of Korean medical science 29.Suppl 3 (2014): S201-S209.


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